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Murine VEGF
货 号：450-32
产品规格：10ug
原 产 地：USA
参考价格：2340 （参考价格，以实际价格为准）
优惠价格：
产品详细信息
Murine VEGF 450-32
别名:
Vascular
Endothelial Growth Factor, VPF, Folliculostellate cell-derived growth
factor, Glioma-derived endothelial cell mitogen, VEGF165
描述:
VEGF
is a potent growth and angiogenic cytokine. It stimulates
proliferation and survival of endothelial cells, and promotes
angiogenesis and vascular permeability. Expressed in vascularized
tissues, VEGF plays a prominent role in normal and pathological
angiogenesis. Substantial evidence implicates VEGF in the induction of
tumor metastasis and intra-ocular neovascular syndromes. VEGF signals
through the three receptors; fms-like tyrosine kinase (flt-1), KDR gene
product (the murine homolog of KDR is the flk-1 gene product) and the
flt4 gene product. Recombinant murine VEGF is a 39.0 kDa
disulfide-linked homodimeric protein consisting of two 165 amino acid
polypeptide chains.
氨基酸序列:
MAPTTEGEQK
SHEVIKFMDV YQRSYCRPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCAGC CNDEALECVP
TSESNITMQI MRIKPHQSQH IGEMSFLQHS RCECRPKKDR TKPEKHCEPC SERRKHLFVQ
DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR
来源:
E.coli
纯度:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
生物活性:
Determined
by the dose-dependent stimulation of the proliferation of human
umbilical vein endothelial cells (HUVEC) using a concentration range of
1.0-5.0 ng/ml.