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Human VEGF165
货 号：100-20
产品规格：10ug
原 产 地：USA
参考价格：2340 （参考价格，以实际价格为准）
优惠价格：
产品详细信息
Human VEGF165 100-20
别名:
Vascular Endothelial Growth Factor, VPF, Folliculostellate cell-derived growth factor, Glioma-derived endothelial cell mitogen
描述:
VEGF
is a potent growth and angiogenic cytokine. It stimulates
proliferation and survival of endothelial cells, and promotes
angiogenesis and vascular permeability. Expressed in vascularized
tissues, VEGF plays a prominent role in normal and pathological
angiogenesis. Substantial evidence implicates VEGF in the induction of
tumor metastasis and intra-ocular neovascular syndromes. VEGF signals
through the three receptors; fms-like tyrosine kinase (flt-1),
KDR gene product (the murine homolog of KDR is the flk-1 gene product)
and the flt4 gene product. Recombinant human VEGF165 is a 38.2 kDa disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains.
氨基酸序列:
APMAEGGGQN
HHEVVKFMDV YQRSYCHPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCGGC CNDEGLECVP
TEESNITMQI MRIKPHQGQH IGEMSFLQHN KCECRPKKDR ARQENPCGPC SERRKHLFVQ
DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR
来源:
E.coli
纯度:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
生物活性:
Determined
by the dose-dependent stimulation of the proliferation of human
umbilical vein endothelial cells (HUVEC) using a concentration range of
1.0-8.0 ng/ml.