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Human GM-CSF
货 号:300-03
产品规格:20ug
原 产 地:USA
参考价格:2340 (参考价格,以实际价格为准)
优惠价格:
产品详细信息
Human GM-CSF 300-03
别名:
Granulocyte/Macrophage Colony-Stimulating Factor, CSF-2, MGI-1GM, pluripoietin-α
描述:
GM-CSF
is a hematopoietic growth factor that stimulates the development of
neutrophils and macrophages and promotes the proliferation and
development of early erythroid megakaryocytic and eosinophilic
progenitor cells. It is produced in endothelial cells, monocytes,
fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and
enhances the functional activity of the mature end-cells. The human
and murine molecules are species-specific and exhibit no cross-species
reactivity. Recombinant human GM-CSF is a 14.6 kDa globular protein
consisting of 128 amino acids containing two intramolecular disulfide
bonds and two potential N-linked glycosylation sites.
氨基酸序列:
MAPARSPSPS
TQPWEHVNAI QEARRLLNLS RDTAAEMNET VEVISEMFDL QEPTCLQTRL ELYKQGLRGS
LTKLKGPLTM MASHYKQHCP PTPETSCATQ IITFESFKEN LKDFLLVIPF DCWEPVQE
来源:
E.coli
纯度:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
生物活性:
The ED50 as determined by the dose-dependent stimulation of the proliferation of
human TF-1 cells is ≤ 0.1 ng/ml, corresponding to a specific activity
of ≥ 1 x 107 units/mg.