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Murine FGF-basic小鼠BFGF
货 号：450-33
产品规格：10ug
原 产 地：USA
参考价格：960 （参考价格，以实际价格为准）
优惠价格：
产品详细信息
Murine FGF-basic小鼠BFGF 450-33
别名:
Fibroblast Growth Factor-basic, FGF-2, HBGF-2, Prostatropin
描述:
FGF-basic
is one of 23 known members of the FGF family. Proteins of this family
play a central role during prenatal development, postnatal growth and
regeneration of a variety of tissues, by promoting cellular
proliferation and differentiation. FGF-basic is a non-glycosylated
heparin binding growth factor that is expressed in the brain, pituitary,
kidney, retina, bone, testis, adrenal gland, liver, monocytes,
epithelial cells and endothelial cells. FGF-basic signals through FGFR
1b, 1c, 2c, 3c and 4. Recombinant Murine FGF-basic is a 16.3 kDa
protein consisting of 145 amino acid residues.
氨基酸序列:
PALPEDGGAA
FPPGHFKDPK RLYCKNGGFF LRIHPDGRVD GVREKSDPHV KLQLQAEERG VVSIKGVCAN
RYLAMKEDGR LLASKCVTEE CFFFERLESN NYNTYRSRKY SSWYVALKRT GQYKLGSKTG
PGQKAILFLP MSAKS
来源:
E.coli
纯度:
Greater than 95% by SDS-PAGE gel and HPLC analyses.
生物活性:
Assay #1: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by
BaF3 cells expressing FGF receptors is ≤ 0.1 ng/ml corresponding to a
specific activity of ≥ 1 x 107 units/mg.
Assay #2: The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 106 units/mg.
Assay #2: The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 106 units/mg.