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Human IL-3
货 号:200-03
产品规格:10ug
原 产 地:USA
参考价格:2340 (参考价格,以实际价格为准)
优惠价格:
产品详细信息
Human IL-3 200-03
别名:
MCGF (Mast cell growth factor), Multi-CSF, HCGF, P-cell stimulation factor
描述:
IL-3
is a hematopoietic growth factor that promotes the survival,
differentiation and proliferation of committed progenitor cells of the
megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil
and mast cell lineages. Produced by T cells, mast cells and
eosinophils, IL-3 enhances thrombopoieses, phagocytosis, and
antibody-mediated cellular cytotoxicity. Its ability to activate
monocytes suggests that IL-3 may have additional immunoregulatory roles.
Many of the IL-3 activities depend upon co-stimulation with other
cytokines. IL-3 is species-specific, variably glycosylated cytokine.
Recombinant human IL-3 is a 15.0 kDa globular protein containing 133
amino acid residues.
氨基酸序列:
APMTQTTSLK
TSWVNCSNMI DEIITHLKQP PLPLLDFNNL NGEDQDILME NNLRRPNLEA FNRAVKSLQN
ASAIESILKN LLPCLPLATA APTRHPIHIK DGDWNEFRRK LTFYLKTLEN AQAQQTTLSL AIF
来源:
E.coli
纯度:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
生物活性:
The ED50 as determined by the dose-dependent stimulation of the proliferation of
human TF-1 cells is ≤ 0.1 ng/ml, corresponding to a specific activity
of ≥ 1 x 107 units/mg.