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Human IL-1alpha人白介素1α
货 号：200-01A-10ug
产品规格：10ug
原 产 地：USA
参考价格：2340 （参考价格，以实际价格为准）
优惠价格：
产品详细信息
Human IL-1alpha人白介素1α peprotech200-01A
产品编号:
200-01A
别名:
Hematopoietin-1,
Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte
Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)
描述:
IL-1α
is a non-secreted proinflammatory cytokine produced in a variety of
cells including monocytes, tissue macrophages, keratinocytes and other
epithelial cells. Both IL-1α and IL-1β binds to the same receptor and
has similar if not identical biological properties. These cytokines
have a broad range of activities including, stimulation of thymocyte
proliferation, by inducing IL-2 release, B-cell maturation and
proliferation, mitogenic FGF-like activity and the ability to stimulate
the release of prostaglandin and collagenase from synovial cells.
However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a
cell-associated cytokine. Recombinant human IL-1α is an 18.0 kDa
protein containing 159 amino acid residues.
氨基酸序列:
SAPFSFLSNV
KYNFMRIIKY EFILNDALNQ SIIRANDQYL TAAALHNLDE AVKFDMGAYK SSKDDAKITV
ILRISKTQLY VTAQDEDQPV LLKEMPEIPK TITGSETNLL FFWETHGTKN YFTSVAHPNL
FIATKQDYWV CLAGGPPSIT DFQILENQA
来源:
E.coli
纯度:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
生物活性:
The ED50 as determined by the dose-dependent stimulation of murine D10S cells is
≤ 0.001 ng/ml, corresponding to a specific activity of ≥ 1 x 109 units/mg.