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Anti-Human CD10 FITC

货  号:11-0108-42

产品规格:100tests

原  产  地:USA

参考价格:2388 (参考价格,以实际价格为准)

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产品详细信息

Anti-Human CD10 FITC

11-0108-42
100tests

USA

The eBioSN5c monoclonal antibody recognizes human CD10 (CALLA, NEP,enkephalinase, Neprilysin),

which is a 100 kDa, type II cell surface glycoprotein originallyidentified for its expression
on most acute lymphoblastic leukemias (ALLs). Subsequently, CD10 wasshown to be the same molecule
as neutral endopeptidase (NEP), or KII-NA. CD10 is a Zn2+-dependent metallopeptidase acting on
substrates such as endothelin, glucagon, gastrin, neurotensin andbradykinin. CD10 is involved
in the regulation of chemotactic and inflammatory processes involvingneutrophils. In B cells,
CD10 regulates stromal cell-dependent B lymphopoiesis and itsexpression has been reported on
mature germinal center B cells. CD10 expression is also found on normaldonor granulocytes and
bone marrow stromal cells. Most likely, CB-CALLA and eBioSN5c seedifferent epitopes due to
their ability to co-stain.
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