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Anti-Human CD10 FITC
货 号:11-0108-42
产品规格:100tests
原 产 地:USA
参考价格:2388 (参考价格,以实际价格为准)
优惠价格:
产品详细信息
Anti-Human CD10 FITC
11-0108-42
100tests
USA
The eBioSN5c monoclonal antibody recognizes human CD10 (CALLA, NEP,enkephalinase, Neprilysin),
which is a 100 kDa, type II cell surface glycoprotein originallyidentified for its expressionon most acute lymphoblastic leukemias (ALLs). Subsequently, CD10 wasshown to be the same molecule
as neutral endopeptidase (NEP), or KII-NA. CD10 is a Zn2+-dependent metallopeptidase acting on
substrates such as endothelin, glucagon, gastrin, neurotensin andbradykinin. CD10 is involved
in the regulation of chemotactic and inflammatory processes involvingneutrophils. In B cells,
CD10 regulates stromal cell-dependent B lymphopoiesis and itsexpression has been reported on
mature germinal center B cells. CD10 expression is also found on normaldonor granulocytes and
bone marrow stromal cells. Most likely, CB-CALLA and eBioSN5c seedifferent epitopes due to
their ability to co-stain.