Anti-Human/Non-Human Primate CD18 FITC

11-0189-42
100tests

USA

The 6.7 monoclonal antibody reacts with human and non-human

primate (rhesus or cynomologus) CD18, which is also known as beta2integrin. CD18 is a 90-95
kDa type I transmembrane protein that heterodimerizes with the a chainof CD11a, CD11b
and CD11c. The CD18/CD11a complex is also known as lymphocyte function-associated
antigen-1 (LFA-1) and plays an important role in cellular adhesion and inflammatory
reactions. CD18 is expressed broadly by human lymphocytes andmonocytes. Peripheral blood
granulocytes also express CD18, but at lower levels.

The 6.7 monoclonal antibody has been reported to induce theproliferation of resting
Tcells cultured with monocytes.