Anti-Mouse CD19 FITC

11-0191-82

100ug

USA

The MB19-1 monoclonal antibody reacts with mouse CD19, a 95 kDa transmembrane

glycoprotein. CD19 is expressed by B cells during all stages of development
excluding the terminally differentiated plasma cells. Folliculardendritic cells also
express CD19. Together CD21, CD81, MHC class II, and CD19 form amultimolecular complex
that associates with the BCR. Signaling through CD19 induces tyrosine phosphorylation,
calcium flux and proliferation of B cells. Staining of B cells withMB19-1 and its conjugates
is usually dimmer than the rat anti-mouse CD19 antibody, clone 6D5.