Anti-Human CD32 FITC

11-0329-41

25tests

USA

This 6C4 monoclonal antibody reacts with human CD32 (also known as Fc gammaRII).

This antibody recognizes two isoforms of the receptor, Fc gammaRIIA andFc gammaRIIB.
These 40-kDa polymorphic transmembrane glycoproteins are expressed on Bcells, granulocytes,
monocytes, macrophages, and platelets. Moreover, these receptors aredetected on natural killer
cells. CD32 enables interaction between Fc gammaRII-expressing cellsand opsonized antigen
or IgG-containing immune complexes. Both receptors exhibit low affinitytowards IgG and play
a role in inflammation and autoimmune disease. This clone has beenreported to inhibit Ig
binding in a rosette blocking assay.