Anti-Human CD267 (TACI) PE  12-9217-41

Also known as: TNFRSF13B
Clone: 11H3
RUO: For Research Use Only. Not for use in diagnostic procedures.
Host     Mouse
Isotype     IgG2a
Reactivity     Human
Conjugate     PE
Laser     Blue Laser, Green Laser, Yellow-Green Laser
Emit     575 nm
Excite     488 - 561 nm
Reported Applications     Flow Cytometric Analysis

References: von Bulow GU, van Deursen JM, Bram RJ. Regulation of the T-independent humoral response by TACI.Immunity. 2001 May;14(5):573-82.

Ng LG, Sutherland AP, Newton R, Qian F, Cachero TG, Scott ML, Thompson JS, Wheway J, Chtanova T, Groom J, Sutton IJ, Xin C, Tangye SG, Kalled SL, Mackay F, Mackay CR. B cell-activating factor belonging to the TNF family (BAFF)-R is the principal BAFF receptor facilitating BAFF costimulation of circulating T and B cells.J Immunol. 2004 Jul 15;173(2):807-17.

Novak AJ, Darce JR, Arendt BK, Harder B, Henderson K, Kindsvogel W, Gross JA, Greipp PR, Jelinek DF. Expression of BCMA, TACI, and BAFF-R in multiple myeloma: a mechanism for growth and survival.Blood. 2004 Jan 15;103(2):689-94.

Sakurai D, Kanno Y, Hase H, Kojima H, Okumura K, Kobata T. TACI attenuates antibody production costimulated by BAFF-R and CD40. Eur J Immunol. 2007 Jan;37(1):110-8. PubMed

Sakurai D, Hase H, Kanno Y, Kojima H, Okumura K, Kobata T. TACI regulates IgA production by APRIL in collaboration with HSPG. Blood. 2007 Apr 1;109(7):2961-7. PubMed

Seshasayee D, Valdez P, Yan M, Dixit VM, Tumas D, Grewal IS. Loss of TACI causes fatal lymphoproliferation and autoimmunity, establishing TACI as an inhibitory BLyS receptor.Immunity. 2003 Feb;18(2):279-88.

Yan M, Wang H, Chan B, Roose-Girma M, Erickson S, Baker T, Tumas D, Grewal IS, Dixit VM. Activation and accumulation of B cells in TACI-deficient mice.Nat Immunol. 2001 Jul;2(7):638-43.