Anti-Human CD289 (TLR9) PE   12-9099-80

Also known as: TLR-9, toll-like receptor 9
Clone: eB72-1665
RUO: For Research Use Only. Not for use in diagnostic procedures.
Host     Rat
Isotype     IgG2a, kappa
Reactivity     Human
Conjugate     PE
Laser     Blue Laser, Green Laser, Yellow-Green Laser
Excite     488 - 561 nm
Reported Applications     Intracellular Staining Followed by Flow Cytometric Analysis

References: Peduzzi E, Groeper C, et al. 2007. Local activation of the innate immune system in Buruli ulcer lesions. J Invest Dermatol. 127(3):638-45. (eB72-1665, IHC paraffin, PubMed)

Jozsef L, Khreiss T, El Kebir D, Filep JG. Activation of TLR-9 induces IL-8 secretion through peroxynitrite signaling in human neutrophils. J Immunol. 2006 Jan 15;176(2):1195-202. (eB72-1665, FC, PubMed)

Schroeder JT, Bieneman AP, et al. 2005. TLR9- and FcepsilonRI-mediated responses oppose one another in plasmacytoid dendritic cells by down-regulating receptor expression. J Immunol. 175(9):5724-31. (eB72-1665, WB, PubMed)

Dasari P, Nicholson IC, et al. 2005. Expression of toll-like receptors on B lymphocytes. Cell Immunol. 236(1-2):140-5. (eB72-1665, IC flow, PubMed)

Latz E, Schoenemeyer A, Visintin A, Fitzgerald KA, Monks BG, Knetter CF, Lien E, Nilsen NJ, Espevik T, Golenbock DT. 2004. TLR9 signals after translocating from the ER to CpG DNA in the lysosome. Nat Immunol. 5(2):190-8.

Juliane Platz, Christoph Beisswenger, Alexander Dalpke, Rembert Koczulla, Olaf Pinkenburg, Claus Vogelmeier, and Robert Bals. 2004. Microbial DNA Induces a Host Defense Reaction of Human Respiratory Epithelial Cells. J. Immunol. 173: 1219 - 1223.

Leifer CA, Kennedy MN, et al. 2004. TLR9 is localized in the endoplasmic reticulum prior to stimulation. J Immunol. 173(2):1179-83. (Immunofluorescence and IP, PubMed)