Anti-Human/Mouse phospho-STAT4 (Y693) PE   12-9044-41

Also known as: Signal transducer and activator of transcription 4
Clone: 4LURPIE
RUO: For Research Use Only. Not for use in diagnostic procedures.
Host     Mouse
Isotype     IgG1, kappa
Reactivity     Human, Mouse
Conjugate     PE
Laser     Blue Laser, Green Laser, Yellow-Green Laser
Emit     578 nm
Excite     488 - 561 nm
Reported Applications     Intracellular Staining Followed by Flow Cytometric Analysis

References: Saraiva M, Christensen JR, Veldhoen M, Murphy TL, Murphy KM, O'Garra A. Interleukin-10 production by Th1 cells requires interleukin-12-induced STAT4 transcription factor and ERK MAP kinase activation by high antigen dose. Immunity. 2009 Aug 21;31(2):209-19.

Ramos HJ, Davis AM, George TC, Farrar JD. IFN-alpha is not sufficient to drive Th1 development due to lack of stable T-bet expression. J Immunol. 2007 Sep 15;179(6):3792-803.

Berenson LS, Gavrieli M, Farrar JD, Murphy TL, Murphy KM. Distinct characteristics of murine STAT4 activation in response to IL-12 and IFN-alpha. J Immunol. 2006 Oct 15;177(8):5195-203.

Harrington LE, Hatton RD, Mangan PR, Turner H, Murphy TL, Murphy KM, Weaver CT. Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol. 2005 Nov;6(11):1123-32.