Anti-Human/Mouse CD266 (TWEAK Receptor) PE   12-9018-42

Also known as: TNFRSF12A , TWEAKR, Fibroblast growth factor-inducible 14, Fn14
Clone: ITEM-4
RUO: For Research Use Only. Not for use in diagnostic procedures.
Host     Mouse
Isotype     IgG2b, kappa
Reactivity     Human, Mouse
Conjugate     PE
Laser     Blue Laser, Green Laser, Yellow-Green Laser
Excite     488 - 561 nm
Reported Applications     Flow Cytometric Analysis

References: Roos C, Wicovsky A, Müller N, Salzmann S, Rosenthal T, Kalthoff H, Trauzold A, Seher A, Henkler F, Kneitz C, Wajant H. Soluble and transmembrane TNF-like weak inducer of apoptosis differentially activate the classical and noncanonical NF-kappa B pathway. J Immunol. 2010 Aug 1;185(3):1593-605. (ITEM-4, FA blocking, PubMed)

Moreno JA, Muñoz-García B, Martín-Ventura JL, Madrigal-Matute J, Orbe J, Páramo JA, Ortega L, Egido J, Blanco-Colio LM The CD163-expressing macrophages recognize and internalize TWEAK: potential consequences in atherosclerosis. Atherosclerosis. 2009 Nov;207(1):103-10 (ITEM-4, WB, PubMed)

Nakayama, M., K. Ishidoh, Y. Kojima, N. Harada, E. Kominami, K. Okumura, H. Yagita. Fibroblast Growth Factor-Inducible 14 Mediates Multiple Pathways of TWEAK-Induced Cell Death. J Immunol. 2003, 170: 341-348.

Harada N., M. Nakayama, H. Nakano, Y. Fukuchi, H. Yagita, K. Okumura. Pro-inflammatory Effect of TWEAK/Fn14 Interaction on Human Umbilical Vein Endothelial Cells. Biochem Biophys Res Commun, 2002, 299(3):488-93.

Nakayama M, K. Ishidoh, N. Kayagaki, Y. Kojima, N. Yamaguchi, H. Nakano, E. Kominami, K. Okumura, H. Yagita. Multiple pathways of TWEAK-induced cell death. J Immunol, 2002, 168(2):734-43