Anti-Human CD257 (BAFF, BLyS) PE   12-9017-41 25 tests

Also known as: TNFSF13B, BLYS, TALL-1, TALL1, THANK
Clone: 1D6
RUO: For Research Use Only. Not for use in diagnostic procedures.
Host     Mouse
Isotype     IgG1, kappa
Reactivity     Human
Conjugate     PE
Laser     Blue Laser, Green Laser, Yellow-Green Laser
Excite     488 - 561 nm
Reported Applications     Flow Cytometric Analysis

References: Kayagaki, N., M. Yan, et al. 2002. BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-kappaB2. Immunity 17(4): 515-24.

Roschke, V., S. Sosnovtseva, et al. 2002. BLyS and APRIL form biologically active heterotrimers that are expressed in patients with systemic immune-based rheumatic diseases. J Immunol 169(8): 4314-21.

Hsu, B. L., S. M. Harless, et al. 2002. Cutting edge: BLyS enables survival of transitional and mature B cells through distinct mediators. J Immunol 168(12): 5993-6.

Yan, M., J. R. Brady, et al. 2001. Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with severe B cell deficiency. Curr Biol 11(19): 1547-52.

Hase H, Kanno Y, Kojima M, Hasegawa K, Sakurai D, Kojima H, Tsuchiya N, Tokunaga K, Masawa N, Azuma M, Okumura K, Kobata T. 2004. BAFF/BLyS can potentiate B-cell selection with the B-cell coreceptor complex. Blood. 103(6):2257-65.