Anti-Human/Mouse phospho-SYK (Y348) PE  12-9014-41

Also known as: Spleen tyrosine kinase, p72-Syk
Clone: moch1ct
RUO: For Research Use Only. Not for use in diagnostic procedures.
Host     Mouse
Isotype     IgG1, kappa
Reactivity     Human, Mouse
Conjugate     PE
Laser     Blue Laser, Green Laser, Yellow-Green Laser
Excite     488 - 561 nm
Reported Applications     Intracellular Staining Followed by Flow Cytometric Analysis

References: Mócsai A, Ruland J, Tybulewicz VL. The SYK tyrosine kinase: a crucial player in diverse biological functions. Nat Rev Immunol. 2010 Jun;10(6):387-402.

Dennehy KM, Ferwerda G, Faro-Trindade I, Pyz E, Willment JA, Taylor PR, Kerrigan A, Tsoni SV, Gordon S, Meyer-Wentrup F, Adema GJ, Kullberg BJ, Schweighoffer E, Tybulewicz V, Mora-Montes HM, Gow NA, Williams DL, Netea MG, Brown GD. Syk kinase is required for collaborative cytokine production induced through Dectin-1 and Toll-like receptors. Eur J Immunol. 2008 Feb;38(2):500-6.

Palacios EH, Weiss A. Distinct roles for Syk and ZAP-70 during early thymocyte development. J Exp Med. 2007 Jul 9;204(7):1703-15.

Cornall RJ, Cheng AM, Pawson T, Goodnow CC. Role of Syk in B-cell development and antigen-receptor signaling. Proc Natl Acad Sci U S A. 2000 Feb 15;97(4):1713-8.