Anti-Human/Mouse phospho-S6 Ribosomal (S235/S236) PE   12-9007-41

Also known as: 40S ribosomal protein S6, Phosphoprotein NP33
Clone: cupk43k
RUO: For Research Use Only. Not for use in diagnostic procedures.
Host     Mouse
Isotype     IgG1, kappa
Reactivity     Human, Mouse
Conjugate     PE
Laser     Blue Laser, Green Laser, Yellow-Green Laser
Excite     488 - 561 nm
Reported Applications     Intracellular Staining Followed by Flow Cytometric Analysis

References: Flotow H, Thomas G. Substrate recognition determinants of the mitogen-activated 70K S6 kinase from rat liver. J Biol Chem. 1992 Feb 15;267(5):3074-8.

Peterson RT, Schreiber SL. Translation control: connecting mitogens and the ribosome. Curr Biol. 1998 Mar 26;8(7):R248-50.

Shah OJ, Hunter T. Critical role of T-loop and H-motif phosphorylation in the regulation of S6 kinase 1 by the tuberous sclerosis complex. J Biol Chem. 2004 May 14;279(20):20816-23.

Jastrzebski K, Hannan KM, Tchoubrieva EB, Hannan RD, Pearson RB. Coordinate regulation of ribosome biogenesis and function by the ribosomal protein S6 kinase, a key mediator of mTOR function. Growth Factors. 2007 Aug;25(4):209-26.