Anti-Human IL-23 p19 PE   12-7823-41

Host     Mouse
Isotype     IgG2b, kappa
Reactivity     Human
Conjugate     PE
Laser     Blue Laser, Green Laser, Yellow-Green Laser
Excite     488 - 561 nm
Reported Applications     Flow Cytometric Analysis

References: Kalim KW, Groettrup M. Prostaglandin E2 inhibits IL-23 and IL-12 production by human monocytes through down-regulation of their common p40 subunit. Mol Immunol. 2013 Mar;53(3):274-82 (23dcdp, FC, PubMed)

Brentano F, Ospelt C, Stanczyk J, Gay RE, Gay S, Kyburz D. Abundant expression of the interleukin (IL)23 subunit p19, but low levels of bioactive IL23 in the rheumatoid synovium: differential expression and Toll-like receptor-(TLR) dependent regulation of the IL23 subunits, p19 and p40, in the rheumatoid arthritis. Ann Rheum Dis. 2009 Jan; 68(1): 143-50.\\\\ Dennehy KM, Willment JA, Williams DL, Brown GD. Reciprocal regulation of IL-23 and IL-12 following co-activation of Dectin-1 and TLR signaling pathways. Eur J Immunol. 2009 May;39(5): 1379-86\\\\Hillyen P, Larche MJ, Bowman EP, McClanahan TK, de Waal Malefyt R, Schewitz LP, Giddins G, Feldmann M, Kastelein RA, Brennan FM. Investigating the role of the interleukin-23/-17A axis in rheumatoid arthritis. Rheumatology. 2009; 48: 1581-9\\\\Goriely S., Neurath MF., and Goldman M. How microorganisms tip the balance between interleukin-12 family members. Nat Rev Immunol. 2008 Jan;8(1):81-6