Anti-Human CD1c FITC  11-0015-41

Description: This L161 monoclonal antibody detects CD1c (also known as BDCA-1), a glycoprotein that is noncovalently linked to beta-2 microglobulin on thymocytes and antigen presenting cells such as dendritic and Langerhans cells. This molecule is also expressed on some circulating and marginal zone B cells, as well as in lymph nodes and germinal centers. CD1c is involved in the presentation of lipid antigens such as microbial fatty acids to effector T cells during the adaptive immune response. Finally, alternative splicing gives rise to three different isoforms of CD1c (soluble, membrane, and cytoplasmic/soluble isoforms).

   
Anti-Human CD1c FITC
Also known as: BDCA-1
Clone: L161
RUO: For Research Use Only. Not for use in diagnostic procedures.

Host     Mouse
Isotype     IgG1
Reactivity     Human
Conjugate     FITC
Laser     Blue Laser
Emit     518 nm
Excite     488 nm
Reported Applications     Flow Cytometric Analysis, Immunohistochemical Staining, Immunoprecipitation